Scampini studied at the Conservatory of Milan with maestro Del Fiume.
He made his debut in
1905 at the Martinetti in Garlasco as Cavaradossi.
In 1907, Scampini sang in Buenos Aires at the Teatro de la Opera in Hérodiade. The same year, he sang at the Teatro Massimo in Palermo as Radames and
Scampini made guest appearances all over Italy, Spain, South America and Hungary.
In 1911, he sang at La Scala in Saffo and Simon Boccanegra.
In 1912, he sang at the Costanzi in Rome Manrico.
In 1915, he sang at the Politeama in Pisa Radames.
In 1913, he sang in Budapestas Radames, Riccardo and Manrico.
In 1916, Scampini sang in Spain and Santiago de Chile.
He voluntereed during the first world war. Unfortunately, he lost a leg and was forced to retire from singing.
Scampini settled in Barcelona where he taught singing.
His daughter Brunilde Scampini was a soprano who sang in the 1930s.